New signing Wayne Brown, who arrived at the club on Friday on a loan deal from Hull, could come in.
Striker Steve Howard resumed training on Thursday after illness ruled him out against the Seagulls.
If deemed fit enough, Howard is likely to replace Paul Dickov in the starting line-up and resume his partnership with top scorer Matty Fryatt.
Goalkeeper Paul Henderson (groin), defensive duo Aleksandar Tunchev and Patrick Kisnorbo (both knee) and midfielder Stephen Clemence (ankle and heel) remain on the sidelines.
Northampton boss Stuart Gray could be missing midfielder Giles Coke.
The 22-year-old has suffered a hip injury and may not be ready in time.
However, there could be better news on Liam Davis who is set for surgery on a hernia problem on February 5, as he should continue to play until he goes under the knife.
Adebayo Akinfenwa faces a late fitness test after being withdrawn at half-time at Colchester on Tuesday night with a hamstring problem.
Jason Crowe is also a doubt as he has struggled through training this week with an Achilles tendon injury.
But Paul Rodgers is definitely out of contention after being sent off against Colchester - he must now serve a one-match ban.
Sporting Life